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Histone Deacetylase Inhibitor Therapy in Epithelial Ovarian Cancer

Since epigenetic alterations are believed to be involved in the repression of tumor suppressor genes and promotion of tumorigenesis in ovarian cancers, novel compounds endowed with a histone deacetylase (HDAC) inhibitory activity are an attractive therapeutic approach. In this review, we discuss the...

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Autors principals: Takai, Noriyuki, Narahara, Hisashi
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801002/
https://ncbi.nlm.nih.gov/pubmed/20052384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/458431
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