Combined Molecular Genetic and Cytogenetic Analysis from Single Cells after Isothermal Whole-Genome Amplification

BACKGROUND: Analysis of chromosomal aberrations or single-gene disorders from rare fetal cells circulating in the blood of pregnant women requires verification of the cells’ genomic identity. We have developed a method enabling multiple analyses at the single-cell level that combines verification of...

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Main Authors: Kroneis, Thomas, Geigl, Jochen B., El-Heliebi, Amin, Auer, Martina, Ulz, Peter, Schwarzbraun, Thomas, Dohr, Gottfried, Sedlmayr, Peter
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356848/
https://ncbi.nlm.nih.gov/pubmed/21558453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2011.162131
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