Identification of small gains and losses in single cells after whole genome amplification on tiling oligo arrays

Clinical DNA is often available in limited quantities requiring whole-genome amplification for subsequent genome-wide assessment of copy-number variation (CNV) by array-CGH. In pre-implantation diagnosis and analysis of micrometastases, even merely single cells are available for analysis. However, p...

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Bibliographische Detailangaben
Hauptverfasser: Geigl, Jochen B., Obenauf, Anna C., Waldispuehl-Geigl, Julie, Hoffmann, Eva M., Auer, Martina, Hörmann, Martina, Fischer, Maria, Trajanoski, Zlatko, Schenk, Michael A., Baumbusch, Lars O., Speicher, Michael R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
Methods Online
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731907/
https://ncbi.nlm.nih.gov/pubmed/19541849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp526
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