Whole-genome plasma sequencing reveals focal amplifications as a driving force in metastatic prostate cancer

Genomic alterations in metastatic prostate cancer remain incompletely characterized. Here we analyse 493 prostate cancer cases from the TCGA database and perform whole-genome plasma sequencing on 95 plasma samples derived from 43 patients with metastatic prostate cancer. From these samples, we ident...

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Udgivet i:Nat Commun
Main Authors: Ulz, Peter, Belic, Jelena, Graf, Ricarda, Auer, Martina, Lafer, Ingrid, Fischereder, Katja, Webersinke, Gerald, Pummer, Karl, Augustin, Herbert, Pichler, Martin, Hoefler, Gerald, Bauernhofer, Thomas, Geigl, Jochen B., Heitzer, Ellen, Speicher, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917969/
https://ncbi.nlm.nih.gov/pubmed/27328849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12008
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