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Changes in Colorectal Carcinoma Genomes under Anti-EGFR Therapy Identified by Whole-Genome Plasma DNA Sequencing

Monoclonal antibodies targeting the Epidermal Growth Factor Receptor (EGFR), such as cetuximab and panitumumab, have evolved to important therapeutic options in metastatic colorectal cancer (CRC). However, almost all patients with clinical response to anti-EGFR therapies show disease progression wit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mohan, Sumitra, Heitzer, Ellen, Ulz, Peter, Lafer, Ingrid, Lax, Sigurd, Auer, Martina, Pichler, Martin, Gerger, Armin, Eisner, Florian, Hoefler, Gerald, Bauernhofer, Thomas, Geigl, Jochen B., Speicher, Michael R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967949/
https://ncbi.nlm.nih.gov/pubmed/24676216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004271
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