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Changes in Colorectal Carcinoma Genomes under Anti-EGFR Therapy Identified by Whole-Genome Plasma DNA Sequencing

Monoclonal antibodies targeting the Epidermal Growth Factor Receptor (EGFR), such as cetuximab and panitumumab, have evolved to important therapeutic options in metastatic colorectal cancer (CRC). However, almost all patients with clinical response to anti-EGFR therapies show disease progression wit...

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書誌詳細
主要な著者: Mohan, Sumitra, Heitzer, Ellen, Ulz, Peter, Lafer, Ingrid, Lax, Sigurd, Auer, Martina, Pichler, Martin, Gerger, Armin, Eisner, Florian, Hoefler, Gerald, Bauernhofer, Thomas, Geigl, Jochen B., Speicher, Michael R.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967949/
https://ncbi.nlm.nih.gov/pubmed/24676216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004271
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