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The expanding relevance of nuclear mTOR in carcinogenesis
Deregulated mTOR signaling drives the growth of various human cancers, making mTOR a major target for development of cancer chemotherapeutics. The role of mTOR in carcinogenesis is thought to be largely a consequence of its activity in the cytoplasm, resulting in increased translation of pro-tumorig...
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| Hoofdauteurs: | , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Landes Bioscience
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3356804/ https://ncbi.nlm.nih.gov/pubmed/22067472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.22.18329 |
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