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In vitro repair of DNA hairpins containing various numbers of CAG/CTG trinucleotide repeats
Expansion of CAG/CTG trinucleotide repeats (TNRs) in humans is associated with a number of neurological and neurodegenerative disorders including Huntington’s disease. Increasing evidence suggests that formation of a stable DNA hairpin within CAG/CTG repeats during DNA metabolism leads to TNR instab...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3356785/ https://ncbi.nlm.nih.gov/pubmed/22041023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.10.020 |
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