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Ryanodine Receptor Phosphorylation, Calcium/Calmodulin-dependent Protein Kinase II, and Life-threatening Ventricular Arrhythmias

RyR2 dysfunction, which may result from a variety of mechanisms, has been implicated in the pathogenesis of cardiac arrhythmias and heart failure. In this review, we will discuss the important role of Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) in the regulation of RyR2-mediated Ca(2+) re...

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Detalhes bibliográficos
Main Authors: McCauley, Mark D., Wehrens, Xander H.T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356691/
https://ncbi.nlm.nih.gov/pubmed/22578240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2012.02.004
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