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Targeted Delivery of a Splice-Switching Oligonucleotide by Cationic Polyplexes of RGD-Oligonucleotide Conjugate

Nanoparticle-based delivery has become an important strategy to advance therapeutic oligonucleotides into clinical reality. Delivery by nanocarriers can enhance access of oligonucleotides to their pharmacological targets within cells; preferably, targeting ligands are incorporated into nanoparticles...

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Bibliographic Details
Main Authors: Ming, Xin, Feng, Lan
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356595/
https://ncbi.nlm.nih.gov/pubmed/22497548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300113c
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