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Unconventional Internalization Mechanisms Underlying Functional Delivery of Antisense Oligonucleotides via Cationic Lipoplexes and Polyplexes

There is mounting interest in developing antisense and siRNA oligonucleotides into therapeutic entities; however, this potential has been limited by poor access of oligonucleotides to their pharmacological targets within cells. Transfection reagents, such as cationic lipids and polymers, are commonl...

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Bibliografski detalji
Glavni autori: Ming, Xin, Sato, Katsuya, Juliano, Rudolph L.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133857/
https://ncbi.nlm.nih.gov/pubmed/21571016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.04.029
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