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Unconventional Internalization Mechanisms Underlying Functional Delivery of Antisense Oligonucleotides via Cationic Lipoplexes and Polyplexes
There is mounting interest in developing antisense and siRNA oligonucleotides into therapeutic entities; however, this potential has been limited by poor access of oligonucleotides to their pharmacological targets within cells. Transfection reagents, such as cationic lipids and polymers, are commonl...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3133857/ https://ncbi.nlm.nih.gov/pubmed/21571016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.04.029 |
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