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A high-throughput screen for the engineered production of β-lactam antibiotics

High-throughput screens and selections have had profound impact on our ability to engineer proteins possessing new, desired properties. These methods are especially useful when applied to the modification of existing enzymes to create natural and unnatural products. In an advance upon existing metho...

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Hlavní autoři: Phelan, Ryan M., DiPardo, Benjamin J., Townsend, Craig A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356498/
https://ncbi.nlm.nih.gov/pubmed/22428872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200504g
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