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Definition of the Common and Divergent Steps in Carbapenem β-Lactam Antibiotic Biosynthesis

Approximately 50 naturally occurring carbapenem β-lactam antibiotics are known. All but one of these have been isolated from Streptomyces species and are disubstituted structural variants of a simple core that is synthesized by Pectobacterium carotovorum (Erwinia carotovora), a phylogenetically dist...

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Bibliografske podrobnosti
Main Authors: Bodner, Micah J., Li, Rongfeng, Phelan, Ryan M., Freeman, Michael F., Moshos, Kristos A., Lloyd, Evan P., Townsend, Craig A.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281309/
https://ncbi.nlm.nih.gov/pubmed/21913298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201100366
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