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A chemical screen identifies class A G-protein coupled receptors as regulators of cilia

Normal cilia length and motility are critical for proper cellular function. Prior studies of the regulation of ciliary structure and length have primarily focused on the intraflagellar transport machinery and motor proteins required for ciliary assembly and disassembly. However, several mutants with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Avasthi, Prachee, Marley, Aaron, Lin, Henry, Gregori-Puigjane, Elisabet, Shoichet, Brian K., von Zastrow, Mark, Marshall, Wallace F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356477/
https://ncbi.nlm.nih.gov/pubmed/22375814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200349v
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