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GPR88 Reveals a Discrete Function of Primary Cilia as Selective Insulators of GPCR Cross-Talk

A number of G protein-coupled receptors (GPCRs) localize to primary cilia but the functional significance of cilia to GPCR signaling remains incompletely understood. We investigated this question by focusing on the D1 dopamine receptor (D1R) and beta-2 adrenergic receptor (B2AR), closely related cat...

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Detaylı Bibliyografya
Asıl Yazarlar: Marley, Aaron, Choy, Regina Wai-Yan, von Zastrow, Mark
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732291/
https://ncbi.nlm.nih.gov/pubmed/23936473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070857
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