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Retromer mediates a discrete route of local membrane delivery to dendrites

A fundamental and still largely unresolved question is how neurons achieve rapid delivery of selected signaling receptors throughout the elaborate dendritic arbor. Here we show that this requires a conserved sorting machinery called retromer. Retromer-associated endosomes are distributed within dend...

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Détails bibliographiques
Auteurs principaux: Choy, Regina Wai-Yan, Park, Minjong, Temkin, Paul, Herring, Bruce E., Marley, Aaron, Nicoll, Roger A., von Zastrow, Mark
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029335/
https://ncbi.nlm.nih.gov/pubmed/24698268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.02.018
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