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A chemical screen identifies class A G-protein coupled receptors as regulators of cilia

Normal cilia length and motility are critical for proper cellular function. Prior studies of the regulation of ciliary structure and length have primarily focused on the intraflagellar transport machinery and motor proteins required for ciliary assembly and disassembly. However, several mutants with...

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Detalhes bibliográficos
Main Authors: Avasthi, Prachee, Marley, Aaron, Lin, Henry, Gregori-Puigjane, Elisabet, Shoichet, Brian K., von Zastrow, Mark, Marshall, Wallace F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356477/
https://ncbi.nlm.nih.gov/pubmed/22375814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200349v
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