Transgenic Mice for a Tamoxifen-Induced, Conditional Expression of the Cre Recombinase in Osteoclasts

BACKGROUND: Studies on osteoclasts, the bone resorbing cells, have remained limited due to the lack of transgenic mice allowing the conditional knockout of genes in osteoclasts at any time during development or adulthood. METHODOLOGY/PRINCIPAL FINDING: We report here on the generation of transgenic...

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Autors principals: Sanchez-Fernandez, Maria Arantzazu, Sbacchi, Silvia, Correa-Tapia, Miguel, Naumann, Ronald, Klemm, Jennifer, Chambon, Pierre, Al-Robaiy, Samiya, Blessing, Manfred, Hoflack, Bernard
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356310/
https://ncbi.nlm.nih.gov/pubmed/22624050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037592
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