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Transgenic Mice for a Tamoxifen-Induced, Conditional Expression of the Cre Recombinase in Osteoclasts

BACKGROUND: Studies on osteoclasts, the bone resorbing cells, have remained limited due to the lack of transgenic mice allowing the conditional knockout of genes in osteoclasts at any time during development or adulthood. METHODOLOGY/PRINCIPAL FINDING: We report here on the generation of transgenic...

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Detalhes bibliográficos
Main Authors: Sanchez-Fernandez, Maria Arantzazu, Sbacchi, Silvia, Correa-Tapia, Miguel, Naumann, Ronald, Klemm, Jennifer, Chambon, Pierre, Al-Robaiy, Samiya, Blessing, Manfred, Hoflack, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356310/
https://ncbi.nlm.nih.gov/pubmed/22624050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037592
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