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Tamoxifen-Inducible Podocyte-Specific iCre Recombinase Transgenic Mouse Provides a Simple Approach for Modulation of Podocytes In Vivo

We report the generation and initial characterization of a mouse line expressing tamoxifen-inducible improved Cre (iCre) recombinase (iCre-ER(T2)) under the regulation of NPHS2 (podocin) gene promoter. The resulting transgenic mouse line was named podocin-iCreER(T2) mice. The efficiency of iCre acti...

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Detalhes bibliográficos
Main Authors: Wang, Jinrong, Wang, Yin, Long, Jianyin, Chang, Benny H.J., Wilson, Mathew H., Overbeek, Paul, Danesh, Farhad R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014324/
https://ncbi.nlm.nih.gov/pubmed/20641128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.20635
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