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Transgenic Mice for a Tamoxifen-Induced, Conditional Expression of the Cre Recombinase in Osteoclasts

BACKGROUND: Studies on osteoclasts, the bone resorbing cells, have remained limited due to the lack of transgenic mice allowing the conditional knockout of genes in osteoclasts at any time during development or adulthood. METHODOLOGY/PRINCIPAL FINDING: We report here on the generation of transgenic...

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Bibliografiska uppgifter
Huvudupphovsmän: Sanchez-Fernandez, Maria Arantzazu, Sbacchi, Silvia, Correa-Tapia, Miguel, Naumann, Ronald, Klemm, Jennifer, Chambon, Pierre, Al-Robaiy, Samiya, Blessing, Manfred, Hoflack, Bernard
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356310/
https://ncbi.nlm.nih.gov/pubmed/22624050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037592
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