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Ribonucleotide Reductase Inhibitors: A New Look at an Old Target for Radiosensitization
Ribonucleotide reductase (RR), the rate limiting enzyme in the synthesis and repair of DNA, has been studied as a target for inhibition in the treatment of cancer for many years. While some researchers have focused on RR inhibitors as chemotherapeutic agents, particularly in hematologic malignancies...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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Frontiers Research Foundation
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3356024/ https://ncbi.nlm.nih.gov/pubmed/22655252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2011.00056 |
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