Glycogen Synthesis is Induced in Hypoxia by the Hypoxia-Inducible Factor and Promotes Cancer Cell Survival

The hypoxia-inducible factor 1 (HIF-1), in addition to genetic and epigenetic changes, is largely responsible for alterations in cell metabolism in hypoxic tumor cells. This transcription factor not only favors cell proliferation through the metabolic shift from oxidative phosphorylation to glycolys...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pelletier, Joffrey, Bellot, Grégory, Gounon, Pierre, Lacas-Gervais, Sandra, Pouysségur, Jacques, Mazure, Nathalie M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Research Foundation 2012
Pynciau:
Oncology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355943/
https://ncbi.nlm.nih.gov/pubmed/22649778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00018
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