Glycogen Synthesis is Induced in Hypoxia by the Hypoxia-Inducible Factor and Promotes Cancer Cell Survival

The hypoxia-inducible factor 1 (HIF-1), in addition to genetic and epigenetic changes, is largely responsible for alterations in cell metabolism in hypoxic tumor cells. This transcription factor not only favors cell proliferation through the metabolic shift from oxidative phosphorylation to glycolys...

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Detalhes bibliográficos
Main Authors: Pelletier, Joffrey, Bellot, Grégory, Gounon, Pierre, Lacas-Gervais, Sandra, Pouysségur, Jacques, Mazure, Nathalie M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355943/
https://ncbi.nlm.nih.gov/pubmed/22649778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00018
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