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Conformational Dynamics of Insulin
We have exploited a prandial insulin analog to elucidate the underlying structure and dynamics of insulin as a monomer in solution. A model was provided by insulin lispro (the active component of Humalog(®); Eli Lilly and Co.). Whereas NMR-based modeling recapitulated structural relationships of ins...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Research Foundation
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3355934/ https://ncbi.nlm.nih.gov/pubmed/22649374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2011.00048 |
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