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A divergent INS protein in Caenorhabditis elegans structurally resembles human insulin and activates the human insulin receptor
Caenorhabditis elegans contains a family of putative insulin-like genes proposed to regulate dauer arrest and senescence. These sequences often lack characteristic sequence features of human insulin essential for its folding, structure, and function. Here, we describe the structure and receptor-bind...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196032/ https://ncbi.nlm.nih.gov/pubmed/12654724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1058003 |
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