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Caenorhabditis elegans DAF-2 as a Model for Human Insulin Receptoropathies

Human exome sequencing has dramatically increased the rate of identification of disease-associated polymorphisms. However, examining the functional consequences of those variants has created an analytic bottleneck. Insulin-like signaling in Caenorhabditis elegans has long provided a model to assess...

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Detalles Bibliográficos
Publicado en:G3 (Bethesda)
Main Authors: Bulger, David A., Fukushige, Tetsunari, Yun, Sijung, Semple, Robert K., Hanover, John A., Krause, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217114/
https://ncbi.nlm.nih.gov/pubmed/27856697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.037184
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