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Survival Motor Neuron Affects Plastin 3 Protein Levels Leading to Motor Defects
The actin-binding protein plastin 3 (PLS3) has been identified as a modifier of the human motoneuron disease spinal muscular atrophy (SMA). SMA is caused by decreased levels of the survival motor neuron protein (SMN) and in its most severe form causes death in infants and young children. To understa...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society for Neuroscience
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3355766/ https://ncbi.nlm.nih.gov/pubmed/22496553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5808-11.2012 |
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