Decay in survival motor neuron and plastin 3 levels during differentiation of iPSC-derived human motor neurons

Spinal muscular atrophy (SMA) is a neuromuscular disease caused by mutations in Survival Motor Neuron 1 (SMN1), leading to degeneration of alpha motor neurons (MNs) but also affecting other cell types. Induced pluripotent stem cell (iPSC)-derived human MN models from severe SMA patients have shown r...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Boza-Morán, María G, Martínez-Hernández, Rebeca, Bernal, Sara, Wanisch, Klaus, Also-Rallo, Eva, Le Heron, Anita, Alías, Laura, Denis, Cécile, Girard, Mathilde, Yee, Jiing-Kuan, Tizzano, Eduardo F., Yáñez-Muñoz, Rafael J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650562/
https://ncbi.nlm.nih.gov/pubmed/26114395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11696
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