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α-COP binding to the survival motor neuron protein SMN is required for neuronal process outgrowth
Spinal muscular atrophy (SMA), a heritable neurodegenerative disease, results from insufficient levels of the survival motor neuron (SMN) protein. α-COP binds to SMN, linking the COPI vesicular transport pathway to SMA. Reduced levels of α-COP restricted development of neuronal processes in NSC-34 c...
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| Publicado no: | Hum Mol Genet |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4664168/ https://ncbi.nlm.nih.gov/pubmed/26464491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv428 |
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