TNF-α induces upregulation of EGFR expression and signaling in human colonic myofibroblasts

The myofibroblast has recently been identified as an important mediator of tumor necrosis factor-α (TNF-α)-associated colitis and cancer, but the mechanism(s) involved remains incompletely understood. Recent evidence suggests that TNF-α is a central regulator of multiple inflammatory signaling casca...

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Detalles Bibliográficos
Main Authors: Yoo, James, Perez, Citlali Ekaterina Rodriguez, Nie, Wenxian, Edwards, Robert A., Sinnett-Smith, James, Rozengurt, Enrique
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2012
Assuntos:
Hormones and Signaling
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355565/
https://ncbi.nlm.nih.gov/pubmed/22301110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00522.2011
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