TNF-α potentiates lysophosphatidic acid-induced COX-2 expression via PKD in human colonic myofibroblasts

The myofibroblast (MFB) has recently been identified as an important mediator of tumor necrosis factor-α (TNF-α)-associated colitis and cancer, but the mechanism(s) involved remains incompletely understood. Here, we show that treatment of 18Co cells, a model of human colonic MFBs, with TNF-α and lys...

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Main Authors: Rodriguez Perez, Citlali Ekaterina, Nie, Wenxian, Sinnett-Smith, James, Rozengurt, Enrique, Yoo, James
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2011
Teme:
Hormones and Signaling
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074991/
https://ncbi.nlm.nih.gov/pubmed/21292998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00381.2010
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