Protein Kinase D1 Mediates Synergistic MMP-3 Expression induced by TNF-α and Bradykinin in Human Colonic Myofibroblasts()

Stromal myofibroblasts regulate extracellular matrix components through the secretion of matrix metalloproteinases such as MMP-3. Both myofibroblasts and MMP-3 have been implicated in colonic inflammation and cancer but the regulatory signaling mechanism(s) are unknown. Exposure of the human colonic...

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Bibliographic Details
Main Authors: Yoo, James, Perez, Citlali Ekaterina Rodriguez, Nie, Wenxian, Sinnett-Smith, James, Rozengurt, Enrique
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176923/
https://ncbi.nlm.nih.gov/pubmed/21867693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.08.029
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