Protein kinase D mediates synergistic expression of COX-2 induced by TNF-α and bradykinin in human colonic myofibroblasts

Myofibroblasts have recently been identified as major mediators of tumor necrosis factor-α (TNF-α)-associated colitis, but the precise mechanism(s) involved remains incompletely understood. In particular, the possibility that TNF-α signaling cross talks with other proinflammatory mediators, includin...

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Hlavní autoři: Yoo, James, Chung, Christine, Slice, Lee, Sinnett-Smith, James, Rozengurt, Enrique
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2009
Témata:
Receptors and Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793067/
https://ncbi.nlm.nih.gov/pubmed/19794144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00184.2009
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