Fundamentally Distinct Roles of Thyroid Hormone Receptor Isoforms in a Thyrotroph Cell Line Are due to Differential DNA Binding

Thyroid hormones have a profound influence on human development and disease. The hypothalamic-pituitary-thyroid axis involves finely tuned feedback mechanisms to maintain thyroid hormone (TH) levels. Despite the important role of TH-negative feedback in regulating this axis, the mechanism by which t...

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Detalhes bibliográficos
Main Authors: Chiamolera, Maria I., Sidhaye, Aniket R., Matsumoto, Shunichi, He, Qiyi, Hashimoto, Koshi, Ortiga-Carvalho, Tania M., Wondisford, Fredric E.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355539/
https://ncbi.nlm.nih.gov/pubmed/22570333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1290
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