Targeting malignant B cells with an immunotoxin against ROR1

The selective cell surface expression of receptor tyrosine kinase-like orphan receptor 1 (ROR1) in chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL) has made ROR1 a novel and promising target for therapeutic monoclonal antibodies (mAbs). Four mouse mAbs generated by hybridoma technol...

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Bibliographic Details
Main Authors: Baskar, Sivasubramanian, Wiestner, Adrian, Wilson, Wyndham H., Pastan, Ira, Rader, Christoph
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355487/
https://ncbi.nlm.nih.gov/pubmed/22531447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.19870
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