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Paclitaxel synergizes with exposure time adjusted CD22-targeting immunotoxins against B-cell malignancies
CD22-targeted recombinant immunotoxins (rIT) are active in hairy cell leukemia or acute lymphoblastic leukemia (ALL), but not in mantle cell lymphoma (MCL) patients. The goal was to enhance rIT efficacy in vivo and to define a strong combination treatment. Activity of Moxetumomab pasudotox (Moxe) an...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5458156/ https://ncbi.nlm.nih.gov/pubmed/28423727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16141 |
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