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A proprotein convertase/MMP-14 proteolytic cascade releases a novel 40 kDa vasculostatin from tumor suppressor BAI1

Brain angiogenesis inhibitor 1 (BAI1), an orphan GPCR-type seven transmembrane receptor, was recently found mutated or silenced in multiple human cancers and can interfere with tumor growth when overexpressed. Yet, little is known about the molecular mechanisms through which this novel tumor suppres...

詳細記述

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書誌詳細
主要な著者: Cork, Sarah M., Kaur, Balveen, Devi, Narra S., Cooper, Lee, Saltz, Joel H., Sandberg, Eric M., Kaluz, Stefan, Van Meir, Erwin G.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355202/
https://ncbi.nlm.nih.gov/pubmed/22330140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.1
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