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Phosphoinositide Binding by the Toll Adaptor dMyD88 Controls Antibacterial Responses in Drosophila

The cell biological principles that govern innate immune responses in Drosophila are unknown. Here, we report that Toll signaling in flies was dictated by the subcellular localization of the adaptor protein dMyD88. dMyD88 was located at the plasma membrane by a process dependent on a C-terminal phos...

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Détails bibliographiques
Auteurs principaux: Marek, Lorri R., Kagan, Jonathan C.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354765/
https://ncbi.nlm.nih.gov/pubmed/22464168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.01.019
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