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Critical role of the Toll-like receptor signal adaptor protein MyD88 in acute allograft rejection

The Toll-like receptors (TLRs) are recently discovered germline-encoded receptors on APCs that are critically important in innate immune recognition of microbial pathogens. However, their role in solid-organ transplantation is unknown. To explore this role, we employed a skin allograft model using m...

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Detalhes bibliográficos
Main Authors: Goldstein, Daniel R., Tesar, Bethany M., Akira, Shizuo, Lakkis, Fadi G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155048/
https://ncbi.nlm.nih.gov/pubmed/12750407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317573
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