A Genome-Wide Association Study identifies a locus on chromosome 7q22 to influence susceptibility for osteoarthritis

To identify genes involved in osteoarthritis (OA), the most prevalent form of joint disease, we performed a genome-wide association study (GWAS) in which we tested 500,510 Single Nucelotide Polymorphisms (SNPs) in 1341 OA cases and 3496 Dutch Caucasian controls. SNPs associated with at least two OA-...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Kerkhof, Hanneke J.M., Lories, Rik J., Meulenbelt, Ingrid, Jonsdottir, Ingileif, Valdes, Ana M, Arp, Pascal, Ingvarsson, Thorvaldur, Jhamai, Mila, Jonsson, Helgi, Stolk, Lisette, Thorleifsson, Gudmar, Zhai, Guangju, Zhang, Feng, Zhu, Yanyan, van der Breggen, Ruud, Carr, Andrew, Doherty, Michael, Doherty, Sally, Felson, David T., Gonzalez, Antonio, Halldorsson, Bjarni V., Hart, Deborah J., Hauksson, Valdimar B., Hofman, Albert, Ioannidis, John P.A., Kloppenburg, Margreet, Lane, Nancy E., Loughlin, John, Luyten, Frank P., Nevitt, Michael C., Parimi, Neeta, Pols, Huibert A.P., van de Putte, Tom, Rivadeneira, Fernando, Slagboom, Eline P., Styrkársdóttir, Unnur, Tsezou, Aspasia, Zmuda, Joseph, Spector, Tim D., Stefansson, Kari, Uitterlinden, André G., van Meurs, Joyce B.J.
التنسيق: Artigo
اللغة:Inglês
منشور في: 2010
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354739/
https://ncbi.nlm.nih.gov/pubmed/20112360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27184
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