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Structural basis of substrate specificity of bifunctional isocitrate dehydrogenase kinase/phosphatase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulates entry into the glyoxylate bypass by reversibly phosphorylating isocitrate dehydrogenase (ICDH). Based on the recent complex structure of AceK-ICDH from E. coli, we have classified the structures of homodimeric NADP(+)-ICDHs to rationalize...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3354702/ https://ncbi.nlm.nih.gov/pubmed/21870819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200809p |
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