Purification, crystallization and preliminary X-ray analysis of isocitrate dehydrogenase kinase/phosphatase from Escherichia coli

The Escherichia coli aceK gene encodes isocitrate dehydrogenase kinase/phosphatase (EC 2.7.11.5), a bifunctional protein that phosphorylates and dephosphorylates isocitrate dehydrogenase (IDH), resulting in its inactivation and activation, respectively. This reversible (de)phosphorylation directs is...

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Bibliographic Details
Main Authors: Zheng, Jimin, Lee, Daniel C., Jia, Zongchao
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2009
Subjects:
Crystallization Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675605/
https://ncbi.nlm.nih.gov/pubmed/19407397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109014729
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