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Chk2 mediates RITA-induced apoptosis
Reactivation of the p53 tumor-suppressor protein by small molecules like Nutlin-3 and RITA (reactivation of p53 and induction of tumor cell apoptosis) is a promising strategy for cancer therapy. The molecular mechanisms involved in the responses to RITA remain enigmatic. Several groups reported the...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3354051/ https://ncbi.nlm.nih.gov/pubmed/22158418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.182 |
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