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A Significant but Rather Mild Contribution of T286 Autophosphorylation to Ca(2+)/CaM-Stimulated CaMKII Activity
BACKGROUND: Autophosphorylation of the Ca(2+)/calmodulin (CaM)-dependent protein kinase II (CaMKII) at T286 generates partially Ca(2+)/CaM-independent “autonomous” activity, which is thought to be required for long-term potentiation (LTP), a form of synaptic plasticity thought to underlie learning a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3353915/ https://ncbi.nlm.nih.gov/pubmed/22615928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037176 |
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