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A Potent, Versatile Disulfide-Reducing Agent from Aspartic Acid

[Image: see text] Dithiothreitol (DTT) is the standard reagent for reducing disulfide bonds between and within biological molecules. At neutral pH, however, >99% of DTT thiol groups are protonated and thus unreactive. Herein, we report on (2S)-2-amino-1,4-dimercaptobutane (dithiobutylamine or DTB...

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Detaylı Bibliyografya
Asıl Yazarlar: Lukesh, John C., Palte, Michael J., Raines, Ronald T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2012
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353773/
https://ncbi.nlm.nih.gov/pubmed/22353145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja211931f
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