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Ribonuclease-Activated Cancer Prodrug
[Image: see text] Cancer chemotherapeutic agents often have a narrow therapeutic index that challenges the maintenance of a safe and effective dose. Consistent plasma concentrations of a drug can be obtained by using a timed-release prodrug strategy. We reasoned that a ribonucleoside 3′-phosphate co...
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| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American
Chemical Society
2012
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3353771/ https://ncbi.nlm.nih.gov/pubmed/22611478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml2002554 |
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