The NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways

The NS1 protein of influenza virus counters host antiviral defences primarily by antagonizing the type I interferon (IFN) response. Both the N-terminal dsRNA-binding domain and the C-terminal effector domain are required for optimal suppression of host responses during infection. To better understan...

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Hlavní autoři: Tisoncik, Jennifer R., Billharz, Rosalind, Burmakina, Svetlana, Belisle, Sarah E., Proll, Sean C., Korth, Marcus J., García-Sastre, Adolfo, Katze, Michael G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for General Microbiology 2011
Témata:
Animal
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353386/
https://ncbi.nlm.nih.gov/pubmed/21593271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.032060-0
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