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The NS1 Protein of a Human Influenza Virus Inhibits Type I Interferon Production and the Induction of Antiviral Responses in Primary Human Dendritic and Respiratory Epithelial Cells

The NS1 protein of the influenza A virus is a potent virulence factor that inhibits type I interferon (IFN) synthesis, allowing the virus to overcome host defenses and replicate efficiently. However, limited studies have been conducted on NS1 function using human virus strains and primary human cell...

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Main Authors: Haye, Kester, Burmakina, Svetlana, Moran, Thomas, García-Sastre, Adolfo, Fernandez-Sesma, Ana
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698524/
https://ncbi.nlm.nih.gov/pubmed/19403682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02323-08
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