Interferon Regulatory Factor 3 Is Necessary for Induction of Antiviral Genes during Human Cytomegalovirus Infection

Viral infection activates interferon regulatory factor 3 (IRF3), a cofactor for the induction of interferon-stimulated genes (ISGs). The role of IRF3 in the activation of ISGs by human cytomegalovirus (HCMV) is controversial despite the fact that HCMV has consistently been shown to induce ISGs durin...

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Bibliografiske detaljer
Main Authors: DeFilippis, Victor R., Robinson, Bridget, Keck, Thomas M., Hansen, Scott G., Nelson, Jay A., Früh, Klaus J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Cellular Response to Infection
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346858/
https://ncbi.nlm.nih.gov/pubmed/16379004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.1032-1037.2006
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