Interferon Regulatory Factor 3 Is Necessary for Induction of Antiviral Genes during Human Cytomegalovirus Infection

Viral infection activates interferon regulatory factor 3 (IRF3), a cofactor for the induction of interferon-stimulated genes (ISGs). The role of IRF3 in the activation of ISGs by human cytomegalovirus (HCMV) is controversial despite the fact that HCMV has consistently been shown to induce ISGs durin...

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Hlavní autoři: DeFilippis, Victor R., Robinson, Bridget, Keck, Thomas M., Hansen, Scott G., Nelson, Jay A., Früh, Klaus J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Cellular Response to Infection
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346858/
https://ncbi.nlm.nih.gov/pubmed/16379004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.1032-1037.2006
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